CRCL Calculator – Creatinine Clearance (Cockcroft-Gault)
This CRCL Calculator helps estimate Creatinine Clearance (CrCl) using the Cockcroft-Gault formula. It is a crucial tool for evaluating kidney function, especially before prescribing medications that are eliminated by the kidneys. The calculator is widely used in clinical settings for patients with renal impairment.
How to Use the CRCL Calculator
Enter the following patient details:
- Age (in years)
- Weight (in kilograms or pounds)
- Serum Creatinine (mg/dL)
- Gender (male/female)
The calculator uses the Cockcroft-Gault formula to estimate CrCl in mL/min.
Cockcroft-Gault Equation
Creatinine Clearance (mL/min) = [(140 – Age) × Weight (kg)] ÷ [72 × Serum Creatinine]
For females, multiply the result by 0.85.
Note: This formula provides an estimate and is less accurate in cases of extreme weight or age. Use clinical judgment when interpreting results.
Common Use Cases
- Renal dosing of antibiotics (e.g., aminoglycosides, vancomycin)
- Assessing renal function in elderly patients
- Preoperative renal evaluation
- Monitoring chronic kidney disease progression
Why Use a Creatinine Clearance Calculator?
CrCl is a key metric for assessing kidney filtration rate and helps determine the proper drug dose for patients. Incorrect dosing can lead to toxicity or inefficacy. This calculator provides quick, accurate results using standard clinical guidelines.
Frequently Asked Questions (FAQs)
What is Creatinine Clearance?
Creatinine Clearance (CrCl) is a measure of how well the kidneys are filtering waste (creatinine) from the blood.
Is CrCl the same as eGFR?
CrCl and eGFR are both measures of kidney function, but eGFR is normalized for body surface area and often estimated differently.
What weight should I use — actual, ideal, or adjusted?
For obese or underweight patients, adjusted or ideal body weight may provide more accurate CrCl estimates.
Why adjust for gender?
Women typically have lower muscle mass than men, so the Cockcroft-Gault formula multiplies the result by 0.85 for females.
Is this calculator accurate for children?
No. The Cockcroft-Gault formula is not validated for pediatric populations. Use other formulas like Schwartz for children.
Related tools: BMI Calculator, BMR Calculator.